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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH8A1 All Species: 26.97
Human Site: Y341 Identified Species: 53.94
UniProt: Q9H2A2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2A2 NP_072090.1 487 53401 Y341 H L E K V R S Y V K R A L A E
Chimpanzee Pan troglodytes XP_001170111 490 53679 Y344 H L E K V R S Y V K R A L A E
Rhesus Macaque Macaca mulatta XP_001101362 515 55911 Y369 H L E K V R S Y V K R A L A E
Dog Lupus familis XP_533415 487 53149 Y341 H L E K V R S Y I K K A R S E
Cat Felis silvestris
Mouse Mus musculus Q8BH00 487 53645 Y341 H L E K V R S Y V L K A Q T E
Rat Rattus norvegicus P13601 501 54541 I354 D K E Q H A K I L D L I E S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509667 487 53578 Y341 H L Q K V R N Y V R K A R D G
Chicken Gallus gallus P27463 509 55791 I362 D K E Q F Q K I L D L I E S G
Frog Xenopus laevis Q6GNL7 902 99964 Y761 H L D K L I E Y C Q T G V K E
Zebra Danio Brachydanio rerio Q66I21 487 53336 Y341 H L Q K V K G Y I T L A L A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_509203 506 55370 I360 Y E K V K S Y I E L A K K E G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56YU0 501 54342 Q349 G P Q V D K R Q F E K I L S Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.4 86 87.2 N.A. 89.9 38.3 N.A. 80.6 38.3 23.7 74.1 N.A. N.A. N.A. 49.4 N.A.
Protein Similarity: 100 94.2 89.1 95 N.A. 95.4 56.8 N.A. 90.3 55.5 36.5 87.6 N.A. N.A. N.A. 67.1 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 73.3 6.6 N.A. 53.3 6.6 33.3 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 26.6 N.A. 80 33.3 60 80 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 37.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 58.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 0 0 9 59 0 34 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 17 0 9 0 9 0 0 0 0 17 0 0 0 9 0 % D
% Glu: 0 9 59 0 0 0 9 0 9 9 0 0 17 9 59 % E
% Phe: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 9 0 0 0 0 9 0 0 34 % G
% His: 67 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 25 17 0 0 25 0 0 0 % I
% Lys: 0 17 9 67 9 17 17 0 0 34 34 9 9 9 0 % K
% Leu: 0 67 0 0 9 0 0 0 17 17 25 0 42 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 25 17 0 9 0 9 0 9 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 50 9 0 0 9 25 0 17 0 0 % R
% Ser: 0 0 0 0 0 9 42 0 0 0 0 0 0 34 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % T
% Val: 0 0 0 17 59 0 0 0 42 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 67 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _